Building the Body: 2012 - Autumn
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The New Innovator Awards complement ongoing efforts by NIH and its Institutes and Centers to fund early stage investigators through R01 grants, which continue to be the major sources of NIH support for early stage investigators. The H3Africa Initiative is focused on supporting these efforts as part of an effort to promote sustainable research in Africa that will promote health and combat disease. The FOA is intended to support basic behavioral research projects focused on two or more sensory modalities.
Building the Body: 2012 - Autumn
This includes research examining ways in which cognitive or affective processes interact with multisensory input to influence basic behavioral targets. While evidence suggests that sensory input is processed interactively instead of additively, research is less developed regarding how different modalities are integrated for perception and behavioral or social outcomes. Enabling tools, technologies, bioreagents, and innovative analytical approaches will likely be required to achieve the research goals.
The NIH invites applications for projects that will identify and qualify extracellular RNA exRNA -based biomarkers derived from human body fluids, such as blood, saliva, urine, breast milk, amniotic fluid, cerebrospinal fluid, ascites and pleural effusions, in order to diagnose and monitor disease progression and response to therapy. The overall goal of this project is to develop reliable, well-defined and clinically relevant biomarkers derived from extracellular RNA that measure tangible benefits for patients in terms of how they feel, function, and survive in clinical trials.
Appropriate studies under this FOA will identify and validate candidate exRNA-based biomarkers in well-defined patient populations, provide new technologies to monitor biomarkers or establish reliable assays for validated markers. Studies using existing human biospecimen collections are strongly encouraged.
Building the Body: - Autumn by Frank Zane | NOOK Book (eBook) | Barnes & Noble®
This FOA is only for studies related to human biomarkers; animal or other non-human disease model studies are not responsive to this FOA. Extracellular RNA exRNA is present in human body fluids, such as blood, saliva, urine, breast milk, amniotic fluid, cerebrospinal fluid, ascites and pleural effusions. The concept that secreted exRNA can alter target cell phenotypes is emerging as a universal and novel paradigm in intercellular signaling.
In view of this emerging paradigm, the NIH invites applications for projects that will develop novel therapies based on exRNA signaling. The overall goal of this initiative is to develop and demonstrate the potential for clinical utility of exRNAs as therapeutic agents, and to develop tools and technologies to enable engineered RNAs to be packaged into extracellular vesicles or associated with RNA-binding proteins for use as extracellular delivery vehicles.
These projects should include methods for the production, purification, and packaging of specific RNAs and methods to deliver them to target cells via extracellular space. Slight modifications or incremental advances over existing approaches will not be considered responsive to this FOA. Projects resulting from this FOA are expected to serve the FDA by generating relevant findings and data needed to inform the regulation of the manufacture, distribution, and marketing of tobacco products to protect public health.
The goal of the GTEx program is to develop a data and sample resource to study the relationship between genetic variation and gene expression across multiple human reference tissues. By the GTEx program is expected to include genetic variation information from approximately post-mortem donors and gene expression measurements from over 20, tissues.
GTEx will represent a large, rich, and unique resource. This FOA is to develop and apply statistical methods and systems approaches to make maximal use of this data. This includes an appreciation for more comprehensive understandings of the relationships regarding cultural attitudes, beliefs, practices, and processes, on outcomes relevant to human health and wellbeing. Model animal research teams are welcome to apply. The Neuroscience Blueprint is a framework to enhance cooperative activities among 16 NIH Institutes, Centers, and Offices that support research on the nervous system.
The Blueprint aims to develop research tools, resources, and training and to make them available to the neuroscience community. Successful applicants to this FOA will become collaborative participants in this network, receiving both funding and no-cost access to contracted drug discovery services that are not typically available to the academic research community. No-directed pharmacology and toxicology, and Phase I clinical testing.
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Researchers in possession of disease assays and small molecule compounds that show promise for treating nervous system and psychiatric disorders, but that are not yet suitable for clinical testing, are strongly encouraged to apply. This listing of potential future initiatives is meant to provide the earliest possible alert to the field of our research interests and of potential upcoming announcements to solicit that research. While NIMH plans to proceed with these initiatives, their publication and timing are not certain and depend on sufficient funding.
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First Quarter, - Issue 2. Fourth Quarter, - Issue 1. Most Popular 1. Growth strategies for an uncertain world 3. The unit assembles the multi-disciplinary team of neurosurgeons, radiation oncologists, medical physicists and technicians who can focus on treating the diverse needs of a variety of patients.
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Stereotactic radiosurgery, a non-invasive treatment technique for tumors benign and malignant that occur in the brain or spinal column, focuses radiation beams to target a defined tumor with surgical precision. The Tel Aviv Sourasky Medical Center is the leading center in Israel for stereotactic radiation treatments, serving as a national center for stereotactic radiosurgery and pioneering the treatment of spinal lesions in Israel.
TASMC among the four centers to set up a national human tissue bank For the first time in Israel, the Ministry of Health has established a national bank for human tissue, to preserve tissue donated for research and development. TASMC is one of four hospitals in Israel selected by a government tender to take part in this national initiative.
In the first stage, the bank will preserve samples of cancerous growths donated by patients. The ultimate goal is match each patient with the ideal treatment, based on his or her individual profile, using, among other sources, their genetic profile. In order to accomplish this, individual genes and genetic mutations that are expressed in certain diseases must be identified. To this end, as many tissue samples as possible should be collected to enable comparison. The tissue bank will promote disease research progress and the development of more advanced and effective treatments.
According to Dr. We already maintain different cancer-growth databases approved under the Helsinki Accords, but expanding the infrastructure will facilitate wider interdisciplinary group research studies. Professor Yehuda Wolf, Director of the Vascular Surgery Department highlights: "The endovascular hybrid suite has opened up an array of new possibilities for novel and improved procedures, with an emphasis on minimizing invasiveness and improving control.
Equipped with a state-of-the-art angiography imaging system and the latest in operating room gear, this hybrid suite provides the ideal environment for procedures requiring simultaneous use of open surgery and catheter-based vascular and cardiac interventions. In the new suite, we were able to perform these endovascular reconstructions with custom-made fenestrated aortic grafts and chimney procedures. Successful kidney transplant with ABO incompatibility The Medical Center has celebrated another first: a kidney transplant between a donor and recipient with different blood types.
The recipient had type O blood, while his wife, the donor, had type B blood. The patient was discharged from the hospital two weeks after the procedure with normal kidney function.
Theiss literally built some of her new designs as if she were an architect drawing a building or an urban developer planning a city - slowly, stitch by stitch, piece by piece. Quite a few of the geometrical motifs incorporated in her designs have an architectural derivation: zigzags evoke Art Deco patterns decorating the facades of buildings; squares call to mind the rows of windows in minimalist skyscrapers.
Grid and trellis-like textures allude to aerial views of cities with braids twisting and turning, evoking networks of roads, rails and walkways in urban metropolises that connect millions of people everyday. Theiss's new dresses and knitted and crocheted separates can be interpreted as modular geographies for the body: a burgundy dress was made joining together small knitted squares with delicate yet solid metal thread to form a multi-dimensional effect; dense cross-strata formations characterise jumpers and tops, whilst traditional cable knits are reinterpreted, recreating Santiago Calatrava's studies revolving around tension and suspension in their patterns.
The cryptic title of the collection - "P43 Trikotage" - is a reference to the address of a "trikotagen" knitwear factory in Germany I would mention the name of the city. After the registration fee is completed and submitted, there is a redirection to the payment page. The payment can be done online, using a credit or a debit card, or via direct bank transfer. After the payment is confirmed the participant will receive an invoice and a confirmation of the booking.